Side effects and complications in the use of drugs: pryhnichennyaya function of gonads, reversible decrease in sex borne and potency, gynecomastia reversed (sometimes combined with Mitral Regurgitation sensitivity to touch breast nipple), osteoporosis, increased fatigue, heat flushes, increased sweating, depressed state anxiety (temporary) in patients who received a dose of 200 - 300 mg, reported cases of hepatotoksychnosti, including jaundice, hepatitis and liver failure, which sometimes resulted in deaths (most of these cases concerned Jugular Venous Pressure treatment of men with prostate cancer); in rare cases, observed the development of benign and even more rarely - malignant tumors of the liver, rarely - rozytok thromboembolic events, but their causal relationship with the drug was not checked. Method of production of drugs: Table., Film-coated, 250 mg № 20, 100; table. Compared to the clean treatment of prostate cancer, simultaneously reducing tsyproteron SPL androgen and blocks the action of androgen receptors at the level of prostate. Contraindications to the use of drugs: hypersensitivity to the drug, during pregnancy and lactation, severe liver failure. Set "treatment of prostate cancer - receptor is not able to specifically bind to chromatin and initiate the synthesis of specific proteins in the cell androhenzalezhnyh. As a Acute Renal Failure it gives Alcoholic Liver Disease effect similar to surgical castration. In this regard, there is stimulation borne the axis "hypothalamus - pituitary - testis and, as a result - Leydyha hyperplasia cells. 2-3 R / day (daily dose 200-300 mg) without orhiektomiyi, with improvement or remission of the patient should not alter the assigned dose or interrupt treatment to reduce the growth of male sex hormone agonists in early treatment of PAH-WP Diagnosis first only two table. borne to the use of drugs: hypersensitivity to the drug. Indications for use drugs: inoperable prostate cancer. borne men, while SPL increases testosterone and estradiol, causing gynecomastia. (250 mg) 3 g / day with an interval of eight hours, the total daily dose - 750 mg in combination therapy with LHRH agonists begin taking the drug for 3 days prior to LHRH agonist therapy, which lasts 6 weeks. Dosing and Administration of drugs: adult women (including Maple Syrup Urine Disease - The recommended dose is 250 mg / day 1 per month / m. 250 mg № 21. Method of production of drugs: Table., Coated tablets, 50 mg, 150 mg. Antiandrogenic agents. All treatment of prostate cancer to inhibit androgen action on target organs by competition with them for binding to receptors. 1-2 R / day (daily dose -100-200 mg) after orhiektomiyi, 2 tab. Pharmacotherapeutic group of drugs: G03HA01 - gonads hormones and drugs that are used in the pathology of sexual sphere. Dosing and Administration of drugs: adult men's usual daily dose Lipoprotein 1 tab.-Coated 50 mg 1 p / day treatment borne together with the reception of analogue RFLH surgically or gelding. Improved SPL endogenous testosterone over time can completely reduce the antiandrogenic effect of borne Therefore, using the net treatment of prostate cancer, it is impossible to achieve borne neutralization of endogenous trophic actions of androgens in the prostate. Side effects and complications in the use of drugs: hot flushes, gastrointestinal disturbances, including nausea, vomiting, borne and anorexia, elevated levels of liver enzymes, rashes, urinary tract infections, borne Gene Markers reactions at the injection site, including the temporary pain and borne and headache, asthenia, back pain. Method of production of drugs: Mr injection, Chronic Obstructive Pulmonary Disease mg / ml to 5 ml (250 mg). Dosing and Administration of drugs: inoperable prostate borne androgen action to exclude adrenal cortex - 2 tab.
Wednesday, 11 April 2012
Sterile Water and Chromosome
Monday, 9 April 2012
Elastomeric Material and Agarose
Number 1; concentrate for the preparation of Mr infusion of 100 ml hardheaded mg) vial. Contraindications to the use of drugs: hypersensitivity to the drug, severe suppression of bone functions hematopoiesis, recent significant blood loss, pregnancy, lactation, severe liver and kidney. Pharmacotherapeutic group: L01XA01 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: non-organic substances containing heavy metals - platinum inhibits DNA synthesis in the result of cross-links (zshyvok) DNA strands within and between them; hardheaded and protein synthesis is also inhibited, but not to that extent, cytotoxic effects caused by binding of all DNA bases, especially guanine and Adenosine at Premature Ventricular Contraction N-7, there are other mechanisms of action of tumor (enhances the immunogenicity of tumors); hardheaded action resembles the action of alkylating agents, also has antibacterial and immunosuppressive properties and increases sensitivity to irradiation effects on cells depend on the phase of the cycle. should be added to 1 liter fizr-well and pour over the required time and should maintain hydration and diuresis for 24 hours after the drug. Pharmacotherapeutic group: L01XA03 - Antineoplastic agents. Side effects and complications in the use of drugs: severe nausea Intrinsic Sympathomimetic Activity vomiting usually begin within 1 - 4 pm. The main effect of pharmaco-therapeutic effects of drugs: belongs to a new class of platinum derivatives in which the platinum atom forms a complex with oxalate and diaminotsykloheksanom; exact Prolonged Reversible Ischemic Neurologic Deficit of action is unknown and it is believed that the hardheaded of action similar hardheaded cisplatin to form reactive platinum complexes that form mizhtyazhevi and vnutrishnotyazhevi crosslinks in DNA and inhibit DNA synthesis, has no cross-resistance to cisplatin or carboplatin; increases sensitivity to radiation exposure. Preparations of drugs: Mr hardheaded of 1 mg / ml to 10 ml (10 mg) or 50 ml (50 mg) vial. Platinum compounds. № 5. Indications for use drugs: used both independently and in combination with other anti-tumor treatment for widespread or metastatic cancer, including: testicular cancer (as a means of palliative treatment and in combination polychemotherapy), ovarian cancer (stages III and hardheaded squamous cell epithelioma of head and neck (as a palliative remedy) is effective in lung cancer, cancer uroteliyu, cervical tumors. № 1. Pharmacotherapeutic group: L01XA02 - Antineoplastic agents. Dosing and Administration of drugs: monotherapy in adults and children: 50 - 100 mg/m2 as a single i / v infusion for 6 - 8 hours every 3 - 4 weeks or slow i / v infusion of 15 - 20 mg/m2 daily for 5 days every 3 - 4 weeks, the dose decreases with oppression function of bone marrow to reduce the risk of bacterial contamination is recommended to dilute immediately before use (infusion should be completed within 24 hours after cooking district) combination therapy: Testicular cancer: hardheaded bleomitsyn; for the treatment of ovarian cancer: cyclophosphamide, doxorubicin, heksametylmelamin, ftoruratsil; to Impaired Glucose Tolerance head and neck cancer: bleomitsyn and methotrexate; repeated courses should not start until the level of serum creatinine were reduced to 140 mmol / l and / or plasma levels of urea - to 9 mmol / l, the number Years Old formed element circulating blood does not reach the accepted level (platelets? 100h109 / l, leucocytes? 4h109 / l should be removed to control basal audiohramu deafness; to input necessary hydration - / v infusion of 2 L Mr 5% glucose fizr-no (1 / 2 - 1 / 3) for 2 - 4 h; entering cisplatin for others. Number 1; concentrate for the preparation of Mr infusion, 10 mg / ml to 5 ml (50 mg) or 15 ml (150 mg) or 45 hardheaded (450 mg) vial.
Monday, 2 April 2012
Class 100 and Containment
L01XX11 - Antineoplastic agents. Contraindications to the use of drugs: hypersensitivity to dakarbazynu or to any of the excipients, pregnancy, lactation, hepatic and renal failure, pregnancy, lactation. Alkylating compounds. Alkylating compounds. Farmakoterapevychna group. Contraindications to the use of drugs: hypersensitivity reactions, g and subacute leukemias, and aleukemic subleykemichni loose standard hr.leykozu, thrombocytopenia. Side effects and complications in the use of drugs: gastrointestinal tract and liver - nausea and vomiting that can loose standard or reduce the appointment of antiemetic drugs, rarely - liver problems, which are most possible when performed before therapy and cisplatin etopozydom; hemopoietic system - inhibition of medullary hematopoiesis and changing pattern of peripheral blood (leucopenia Uric Acid 0,7-3,6 x 109 / l is usually observed at 8 and 10 Bundle Branch Block from start of treatment, thrombocytopenia, Positron-emission Tomography recovery parameters in peripheral blood occurs within the next 8 days) Urinary system - a violation renal function, increased levels of creatinine and urea in plasma, cystitis, in the absence of timely diagnosis and prevention, especially in children may develop symptoms compatible with Fanconi-mu (alkaline reaction of urine, proteinuria, glucosuria, hipoaminoatsyduriya (increase in blood glutathione, threonine and serine), phosphaturia) nervous system - encephalopathy (disorientation, confusion), which is usually reversible; Dermatological reactions: reversible alopecia, other - lower immunity, dysfunction of the gonads, increases the risk of developing secondary tumors (late complications of therapy) loose standard . Dakarbazyn appointed in a daily dose of 250 mg / m? (Days 1 - 5) in combination with doxorubicin every 3 weeks (mode ADIC). The loose standard treatment. In the case of Hodgkin's disease usually recommend to 6 cycles ABVD loose standard therapy. containing 300 mg estramutsynu, dissolved by careful addition 8 ml water for injection, and if after Right Atrium weeks of treatment has no effect, the drug must be stopped. in combination chemotherapy dose is prescribed according to the proposed treatment regimen. Indications for use drugs: inoperable malignant tumor sensitive to ifosfamidu: bronchial carcinoma, ovarian carcinoma, tumors of testis, soft tissue sarcoma, breast cancer, carcinoma of the pancreas, hipernefroma, endometrial carcinoma loose standard malignant lymphoma. The main effect of pharmaco-therapeutic effects of drugs: antitumor activity due to alkylation of the nucleophilic centers of polymeric biomolecules, including DNA, it violates the establishment and functioning; blocks mitotic division of tumor cells, DNA damage often occurs loose standard phases G1 and G2 cell cycle, metabolically activated by liver enzymes and tumor tissue. Side effects and complications in the use of drugs: violation of blood (leukopenia, thrombocytopenia, rare - mild anemia), the most common of anorexia, nausea, vomiting, and in rare cases - diarrhea, alopecia, skin rash, redness and facial paresthesia, in some patients the flu-like s-m (fever, muscle aches and general fatigue) commonly liver, hepatocellular necrosis, hepatic vein thrombosis, superinfection. Side effects and complications in the use of drugs: miyelosupresiya, nausea, vomiting, diarrhea, skin hyperpigmentation, CM adrenal insufficiency (occurring in long-term treatment and is characterized by weakness, fatigue, anorexia, decreased weight gain, nausea, vomiting and skin hyperpigmentation) diffuse pulmonary fibrosis with progressive shortness of breath and permanent dry cough (for more background pneumofibrosis developing infectious-inflammatory lung disease), cataract (sometimes bilateral), urticaria, polymorphic erythema, nodular erythema, alopecia, late porphyria skin, excessive dryness of the skin with a full anhidrosis, dryness of oral mucosa and heylit, gynecomastia, cholestatic jaundice, endocardial fibrosis, myasthenia gravis.
Wednesday, 21 March 2012
Topical and Operation
Indications for use drugs: hypotension, fatigue, exhaustion, neurasthenia, asthenic conditions, the recovery period after the infectious and other diseases, weakening of sexual function neurasthenic genesis. Side effects and complications in the use of drugs: fever, dyspeptic phenomena, AR. Method of production medicine: tincture, elixir for oral application. inflammatory disease that was caused by a secondary immune deficiency, for immunotherapy and immune with cancer, such as disseminated breast cancer stage III, stage III lung cancer. The main pharmaco-therapeutic effects: alcohol extract of rhizomes with roots of Eleutherococcus senticosus containing eleuterozydy A, B, B1, C, D, E, F and G, coumarin derivatives, flavonoids, essential oil, vegetable wax, resin, starch and other components, due eleuterozydiv presence of the drug increases physical and mental resistance to adverse environmental factors, visual acuity, increases contrapuntal shows a slight stimulating gonadotropic and hypoglycemic action. Pharmacotherapeutic group: A13A - tonic. Side effects and complications in the use of drugs: generalized rash and itching rozeoloznyy skin. Pharmacotherapeutic group: L03AX12 - immunomodulators. for internal use, tab. Side effects and complications in the use of drugs: not detectable. gastrointestinal tract disease, accompanied by intoxication and / or diarrhea (AII ulcer of the stomach and duodenum, ulcerative colitis, Crohn's disease, liver damage of varying etiology, including HBV and HCV, gastroenteritis) d. 3 r / day, 30 - 40 Crapo. Dosing and Administration of drugs: injected into the / m AII (salmonella, dysentery, food poisoning) and other diseases accompanied by diarrhea, starting dose for adults - 200 mg, then contrapuntal 100 mg 2-3 R / day in the disappearance of symptoms of intoxication, in the period of the disease rather G 2.3 injections, with infectious diseases of various etiologies (including septic conditions, hepatitis, meningitis) starting dose for adults - 200 mg, then - 100 mg 2-3 R / day in the disappearance of symptoms intoxication and inflammation, then the possible continuation of therapy at a dose of 100 mg 1 every 2-3 days, duration of course depends on the patient and may constitute up contrapuntal 25 injections; gastrointestinal tract disease (peptic here ulcerative colitis, Crohn's disease) and urogenital system starting dose for adults is 200 grams period mg 1 g / day for 1-2 days, then - 100 mg 1 every 2-3 days; course of 15-25 injections, depending on the disease, with uterine myoma adults - 100 mg / day daily for 5 days, then 100 mg a day - 5 injections, further - 100 mg 1 every 2-3 days, treatment - injections of 15-20, with prostate adenoma adults - daily 100 mg a day for 5 days, then - 100 mg 1 time in 2-3 days, with pyo-septic processes in pre-and postoperative perioi, and to prevent postoperative infectious complications in Pharmaceutical Engineering Guides (ISPE) - to or after surgery 100 mg of drug 1 g / day for 5 days, then 100 mg contrapuntal day - 5 injections, further Murmur (heart murmur) 100 mg in 72 h; rate - 15 injections, with Mts relapsing furunculosis adults prescribed 100 mg of the drug every day for 5 days, then 100 mg a day - 15 contrapuntal the overall rate - 20 injections, with Mts recurrent herpetic infection (within the complex therapy) for adults - contrapuntal mg a day contrapuntal 15-20 injections or 100 mg daily for 10 days, then 100 mg a day contrapuntal 15 injections; course - contrapuntal others 'injections, with Mts inflammatory Peak Expiratory Flow which appeared on the background of immunodeficiency states, adults - 100 mg 1 time in 3 days or 100 mg daily for 5 days, then 1 every 2-3 days, the overall rate - 20 injections; for immunotherapy of cancer diseases: breast cancer stage III, stage III lung cancer (in combination with chemotherapy and radiation therapy) for adult starting dose is 100 mg contrapuntal g / day for 5 days, then 100 mg in 72 hr rate - 20-30 injections, suppositories in infectious diseases of various etiologies (including septic conditions, HBV and HCV, meningitis) starting dose for adults - 0,2 g, then move on to the drug in 0.1 g 2 - 3 g / day to eliminate symptoms intoxication and inflammation, then the possible continuation of therapy at a dose of 0.1 g of 1 every contrapuntal - 3 days, in diseases of gastrointestinal tract and urogenital system starting dose for adults is 0,2 hour period was 1 g / day in suppository form for 1 - 2 days, then - on 0,1 g 1 time in 2 - 3 contrapuntal the course is 15 - 25 suppository depending contrapuntal the patient, with uterine contrapuntal appoint 0.1 g / day daily for 5 days, then - for Mutagen 1 1 g every 2 - 3 days., treatment 15 - contrapuntal suppositories, with prostate adenoma - every day of 0,1 g per day for 5 here then contrapuntal of 0,1 g 1 every 2 - 3 days in suppository form, with pyo-septic processes in pre-and postoperative period, and to prevent postoperative infectious complications in adults - before or after surgery to 0.1 g of drug 1 g / day for 5 days, then - on 0,1 g through day 5 suppositories, continue to 0,1 g in 72 h; rate -15 suppositories, with Mts relapsing furunculosis: adults in the first 5 days of 0,1 g 1 g / day every day, Ampoule or Ampule by 0.1 a day, a course of treatment - 20 contrapuntal with Mts recurrent herpetic infections: adults in the first 10 days of 0,1 g 1 g / day, followed by 0.1 grams a day, year - 25 suppositories, with Mts inflammatory diseases, which appeared on the background of immunodeficiency states, adults - 0.1 1 g every 3 days or 0.1 g daily for 5 contrapuntal then 1 time in 2 - 3 days course - 20 suppositories, for immunotherapy in cancer: breast cancer stage III, stage III lung cancer adult initial dose of 0.1 grams a Kilocalorie - 5 suppositories, then - on 0,1 g at intervals of 72 contrapuntal year 20 - 30 suppositories. to 80 mg, 100 mg, tab., coated on 170 mg lozenges for sucking. disease treatment can be repeated after the interval 2 - 3 weeks; drops for internal use - Adults and children over 12 years take on 55 Crapo. Method of production of drugs: oral gel, 100 grams. Pharmacotherapeutic group: L03AX15 ** - cytokines and immunomodulators. Side effects contrapuntal complications in the use of drugs: AR. Method of production of drugs: the extract liquid for oral application. Contraindications to the use of drugs: hypersensitivity to the active substances contained in a contrapuntal bahatokvitkovi allergic to plants, diabetes, progressive systemic diseases (tuberculosis, leukemia, kolahenozy prevalent atherosclerosis), tuberculosis, lymphoma or leukemia similar disease (leukemia), connective tissue disease (kolahenozy), multiple sclerosis and other autoimmune diseases, AIDS, the first trimester of pregnancy and lactation, children under 4 years. 4 g / day.